Table of contents
Purpose
In this meta-analysis, we aim to compare ketamine use versus a control group (saline solution) during induction of anesthesia in adolescent idiopathic scoliosis patients undergoing fusion surgery in terms of postoperative opioid consumption, pain control, and side effects.
Methods
A PubMed search of studies published over the last 20 years using the descriptor/terms «ketamine AND scoliosis» was performed. Baseline characteristics of each article were obtained and efficacy measures analyzed (morphine equivalent treatment at 24, 48, and 72 h postoperatively, complications [vomiting/nausea and pruritus], length of hospital stay [days]; and pain score [VAS]) (Review Manager 5.4 software package).
Results
Conclusions
The use of intraoperative and postoperative continuous low doses of ketamine significantly reduces opioid use throughout the first 48 h in patients with AIS who undergo posterior spinal fusion.
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